The severe form of COVID-19 was associated with increased CT sores > 50%, NLR > 6, and blood level of CRP > 75 ng/mL, but we found no correlation with gender, older age over 65, smoking, or chronic co-morbidities as hypertension, obesity, and diabetes (Table A4). This evidence concerns the gene CRP and obesity due to melanocortin 4 receptor deficiency.