TNF and psoriasis: An in vitro study showed that TNF-α, in the presence of a high-salt (HS) environment, increases endothelial cell activation in a 3D model of a bifurcating artery under non-uniform shear forces and that this proatherogenic effect of TNF-α was NaCl-concentration-dependent [21], which might be of particular interest in diseases with elevated TNF-α levels, such as psoriasis.