Interestingly, Gong and Wentworth [123] reported the resolution of symptoms of severe binge eating disorder after semaglutide therapy in a 27-year-old woman with class 1 obesity (BMI: 30.1 kg/m2) and long-standing T1D, who was treated with basal-bolus insulin therapy starting from disease diagnosis (at 10 years of age). Here, INS is linked to obesity due to melanocortin 4 receptor deficiency.