FASLG and systemic lupus erythematosus: Known risk factors for adverse events include a poor reproductive history (a history of ≥ four pregnancy losses), a high-risk antibody profile (a higher number of positive aPLs such as triple or double positivity or high aPL titers), concomitant systemic lupus erythematosus and/or other autoimmune diseases, and hypocomplementemia (which appears to be a promising tool to predict APOs in the context of OAPS) [60].