MITF and malignant soft tissue neoplasm: In the latest WHO Classification of Skin Tumors, fifth edition, three new entities were described and added in two different chapters (melanocytic and soft tissue) of the classification and can be recognized as MITF pathway-activated cutaneous melanocytic tumors, and are represented by CRTC1::TRIM11 cutaneous tumors (malignant soft tissue tumors with uncertain differentiation), ACTIN::MITF cutaneous tumors (melanocytic), and MITF::CREM cutaneous tumors (melanocytic) [27,28].