On the other hand, FDRs1 had significantly higher levels of both basal and stimulated C-peptide than patients with T1D in IRS (basal C-pep.: 1.27 ± 0.11 vs. 0.16 ± 0.11 p < 0.001; stimulated C-pep.: 1.91 ± 0.29 vs. 0.35 ± 0.25 p < 0.001; nmol/l), while in CR, C-peptide levels were comparable (1.27 ± 0.11 vs. 0.57 ± 0.27; 1.91 ± 0.29 vs. 1.08 ± 0.48 nmol/l p = 0.13 and p = 0.084, respectively) (Table 2). The gene discussed is IARS1; the disease is type 1 diabetes mellitus.