Furthermore, Banu et al. [68] revealed significantly higher laminin to albumin excretion ratios in T2DM patients with diabetic nephropathy compared to non-diabetic nephropathy patients, and found a positive relationship between urinary LN and tubular dysfunction markers, such as N-acetyl-β-D-glucosaminidase and α-1 microglobulin. This evidence concerns the gene LAMB2 and type 2 diabetes mellitus.