Fragile X syndrome often presents a wide range of neurodevelopmental, behavioral, and psychiatric challenges caused by errors in the FMR1 gene, most often from CGG trinucleotide repeat expansions leading to full mutations by the methylation of the DNA cytosine bases and silencing FMR1 gene translation, with significantly altered levels or reduced or no production of mRNA and encoded FMRP. This evidence concerns the gene FMR1 and fragile X syndrome.