While the roles of these lncRNAs in glioblastoma cells are not well established, ZFAS1 has been shown to promote glioma progression by enhancing proliferation, migration, and invasion and increase resistance to temozolomide in vitro through the miR-150-5p/PLP2 axis, as well as by regulating EMT and Notch signaling pathways [83,84]. The gene discussed is PLP2; the disease is central nervous system cancer.