Although hyperlipidaemia can be explained by compensatory increasing liver protein synthesis due to expressed urinary protein losses and hypoalbuminemia, it has been suggested that SMARCAL1 might also modulate cellular lipid metabolism due to its interaction with a well-known regulator of lipoprotein lipase and endothelial lipase, angiopoietin-like 3 (Angptl3) [36]. Here, ANGPTL3 is linked to hyperlipidemia.