Although its best-known biological function in pigmentation does not hint at a connection with patient survival, a correlation of high TYRP1 mRNA expression with adverse clinical outcomes of MM patients has already been noticed by others [42,68], and it was shown that TYRP1 mRNA sequesters miR-16, thereby repressing its ability to downregulate the expression of target mRNAs involved in MM cell proliferation and tumor growth [69]. The gene discussed is TYRP1; the disease is Miyoshi myopathy.