B2M and chronic kidney disease: In a study comparing Stage G1–3 CKD patients to healthy controls in an Asian population, more urinary proteins were expressed among the healthy controls compared to those with CKD, with lower urinary protein expression occurring in those with advanced stages of CKD, and urinary proteins such as beta-2 microglobulin, Fetuin A, vitamin-D binding globulin, and alpha-1 microglobulin/bikunin precursor were linked to stages with poorer kidney function [5].