A melanocyte-specific zDHHC13 transgenic mouse model was crossed with mice expressing the MC1R R151C variant or MC1R C315S variant (non-palmitoylated) [146]; this model demonstrated that the palmitoylation level of MC1R R151C (as determined via ABE) was markedly increased, suggesting that zDHHC13 can reverse susceptibility to UVB-induced melanoma progression [146]. Here, MC1R is linked to melanoma.