On the contrary, reports on CYP1A1 expression are conflicting, with studies performed in Asia [105,118,125] reporting an increase in CYP1A1 mRNA in AD lesional skin and PBMCs while a study [126] analysing publicly available datasets generated in Western countries [127,128] reports decreased CYP1A1 in AD skin and keratinocytes versus healthy. Here, CYP1A1 is linked to Alzheimer disease.