SIAH2 and breast cancer: Significant differences were identified for ARIH1, SIAH2, UBR5, and WWP2 in breast cancer stages; ARIH1 showed significant differences between Normal and Stages 1, 2, 3, and 4 (p < 0.05) (Figure S3A), as did SIAH2 between Normal and Stages 1, 2, 3, and 4 (p < 0.05) (Figure S3C), UBR5 between Normal and Stages 1, 2, and 3 (p < 0.05) (Figure S3E), and WWP2 between Normal and Stages 2 and 3 (p < 0.05) (Figure S3G).