CD8A and non-small cell lung carcinoma: Similarly, Lawal et al. [132], using NSCLC scRNA-seq datasets, reported that MAP2K1, mTOR, YAP1, and EGFR predominantly localized to monocytes, macrophages, Tregs, and CD8+ T cells, where they contributed to M2 polarization in the tumor microenvironment of both primary and metastatic NSCLC.