NCR1 and diabetes mellitus: Flow cytometry results exhibited that compared to normal mice, the NKp46 expression on the surface of the NK cells of diabetic mice was significantly decreased, and the cytotoxic activity of the NK cells of T1DM mice gradually reduced with the progression of diabetes, which indicated that diabetes would progressively impair the cytotoxic activity of NK cells, which was not conducive to the clearance of injured cells and, thus, increased the risk of complications with DCM.