DEAD-box helicase 17 (DDX17) was recruited by Cphar to bind the CCAAT/enhancer binding protein beta (C/EBP-β), which prevented the transactivation of activating transcription factor 7 (ATF7) by C/EBP-β, thereby inhibiting the expression of ATF7 in cardiomyocytes to suppress myocardial ischemia reperfusion injury and cardiac remodeling, which may contribute to alleviating DCM. This evidence concerns the gene DDX17 and familial dilated cardiomyopathy.