Two main types of zebrafish Parkinson’s models are used in experimental pharmacology, i.e., the neurotoxin-induced (1-methyl-4-phenyl-1,2,3,6-tetra-hydropyridine (MPTP), 6-hydroxydopamine (6-OHDA), paraquat, rotenone, and other neurotoxic agents) and the transgenic model (PTEN Induced Putative Kinase 1 (PINK1), Parkin RBR E3 Ubiquitin Protein Ligase (Parkin), DJ-1, α-synuclein, Parkinson’s disease protein 2, PD protein 7, leucine-rich repeat kinase 2 (LRRK2), and other gene mutations) [180,181]. The gene discussed is LRRK2; the disease is Parkinsonism.