CXCL8 and obesity due to melanocortin 4 receptor deficiency: For the other examined inflammatory biomarkers, the plasma IL-8, PCT, TREM-1, and uPAR concentrations were not correlated with BMI or body weight nor associated with obesity, as the levels of these biomarkers were comparable between obese and non-obese groups, and in all four classes of obesity (Figure 1).