The second one was a group of genes (CENPP, ASPN, NOL8, EPB41L4A, OPCML, ST14, ZBTB44, CPSF2, LGMN, CHCHD3, ZNF512, CCDC121, MRPL33, IQCF6, RAD54L2, DCAF1, TRIM13, SPRYD7, LHFPL6, RCBTB1) associated with various cancer and tumour diseases [42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60]. The gene discussed is OPCML; the disease is cancer.