The first was a group of novel genes (7) and the second was a group of genes associated with various cancer and tumour diseases (TXNDC12, NRDC, MIR761, ITSN2, NCOA1, SCUBE2, DENND5A, RCN2) [82,83,84,85,86,87,88,89]. The gene discussed is SCUBE2; the disease is cancer.