In the AP group, T-AOC (p < 0.01), CAT (p < 0.001), IgM (p < 0.05), C3 (p < 0.05), and IGF-1 (p < 0.01) concentrations increased by 69.13%, 73.71%, 30.30%, 20.36%, and 31.71%, respectively(Figure 2C,D,G,H,T). This evidence concerns the gene CD40LG and alkaline phosphatase measurement.