In COVID-19, immune effector cells secrete high levels of chemokines and proinflammatory cytokines (e.g., TGFβ, TNFα, IL-33, IL-18, IL-12, IFNγ, IL-6, IL-1β, and IFN-α) in response to SARS-CoV-2 infection [7]. The gene discussed is IL1B; the disease is COVID-19.