If a patient with venous thrombosis is treated with therapeutic doses of LMWH and tests positive for aCL IgG/IgM, anti-β2GPI IgG/IgM, or aPS/PT IgG/IgM, or if he has a personal history of venous thrombosis and tests positive for aCL IgG/IgM, anti-β2GPI IgG/IgM, or LA and tests positive again after at least three months, the recommendation is as described below (Figure 2). The gene discussed is APOH; the disease is Venous thrombosis.