Decreases blood glucose, improves glucose tolerance, reduces insulin resistance, lowers HbA1c, TG, TC, increases GLUT4 (glucose transporter 4), PPARα (peroxisome proliferator-activated receptor α), decreases body weight, increases insulin and leptin levels, enhances ApoA-1 (apolipoprotein A-1) levels. This evidence concerns the gene SLC2A4 and Insulin resistance.