NUTM1 (nuclear protein in testis midline carcinoma family 1) rearrangement with transcription factors and epigenetic regulators (ACIN1, BRD9, CUX1, IKZF1, SLC12A6, and ZNF618) occurs in 1–2% of childhood B-ALL cases and has a good prognosis [102]. This evidence concerns the gene IKZF1 and precursor B-cell acute lymphoblastic leukemia.