The factors included age, gender, BMI, T2DM, HT, DLP, AST, ALT, platelet count, liver steatosis grade, PNPLA3 rs738409, TM6SF2 rs58542926, and HSD17B13 rs6834314; as well as VCTE, M2BPGi, FIB-4, APRI, and NFS. The gene discussed is TM6SF2; the disease is Hepatic steatosis.