Additionally, EGCG has been shown to enhance the sensitivity of GBM and various other tumor cells to a range of cytotoxic agents, including TMZ, 5-fluorouracil, taxol, vinblastine, gemcitabine, doxorubicin, paclitaxel, interferon-α2b, and a tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) [107,133]. This evidence concerns the gene TNFSF10 and glioblastoma.