Vicharenko and Rozhko also analyzed levels of interleukin-6 and tumor necrosis factor alpha (TNF-α) in patients with hypertension and periodontitis, considering standard treatment plus chlorhexidine or the same treatment plus medications (Ca-D3 NICOMED, 2 tablets per day; electrophoresis with “Calcium Gluconate” for 10 sessions; Pentoxifylline, 1 tablet three times a day). This evidence concerns the gene IL6 and hypertensive disorder.