NPPB and Huntington disease: In our current study of incident HD, BNP concentrations ≥ 100 pg/mL were associated with an HR for MACE of 1.28 [(1.13–1.44); X2 15.36; p < 0.0001] and an HR for all-cause mortality of 1.28 [(1.20–1.37); X2 58.61; p < 0.0001], which is consistent with results reported for the prevalent HD population.