Human neuroblastoma (Sh-SY5Y) cells, rendered apoptotic with production of unfavorable cytokines by exposure to tumor necrosis factor alpha (TNF-α), experienced restoration of normal metabolism and a marked reduction in unfavorable cytokines when exposed to 450 mg% dextrose [41], and this was replicated with similar findings, including a reduction in reactive oxygen species production [40]. Here, TNF is linked to neuroblastoma.