Similarities observed between 9-HODE/9-HOTrE-treated Cyp2b-null mice compared to hCYP2B6-Tg and Cyp2b-null fasted mice would be interpreted as indicators that 9-HODE/9-HOTrE are a significant reason for the increased steatosis in hCYP2B6-Tg mice. This evidence concerns the gene CYP2B6 and steatosis.