CYP2B6 and steatosis: To further investigate the role of CYP2B6 in the development of steatosis in vivo and compare the effects of individual oxylipins with CYP2B6 activity in mice, hCYP2B6-Tg mice were also subjected to a 20 h fasting period to investigate the development of steatosis compared to Cyp2b-null mice.