The immunoreaction with anti-SGLT2 in the renal tissue was observed at the same level in mice both with no treatment and with malocclusion, whereas the immunoreaction was stronger in STZ-administered mice than in mice without STZ administration, and the immunoreaction in the STZ-administered mice was stronger with malocclusion than without malocclusion (Figure 3). This evidence concerns the gene SLC5A2 and Dental malocclusion.