A number of autoantigens have been found to be associated with T1DM, including insulin (IAA), glutamic-acid decarboxylase (GADA), tyrosine phosphatase-like insulinoma antigen 2 (IA2A), islet cell cytoplasmic proteins (ICA), and β-cell-specific zinc transporter 8 (ZnT8A), which can trigger the development of autoantibodies specifically during this period [85,86]. Here, INS is linked to type 1 diabetes mellitus.