NPPB and intermediate coronary syndrome: Thus, high levels of brain natriuretic peptide (BNP) and atrial natriuretic peptide (ANP) correlate with the presence of left ventricular (LV) systolic and diastolic dysfunction, while fibroblast growth factor 2 (FGF 2) correlates positively with the extent of collateral circulation assessed by coronary angiography and with the risk of unstable angina pectoris.