BRCA1 and Lynch syndrome: For high-risk populations, i.e., women with BRCA1/2 mutations or those with a family history of hereditary syndromes such as the Lynch syndrome, are advised to undergo regular screenings, including a combination of TVUS and serum CA-125 tests, biannually, typically starting at the age of 30, especially for those with BRCA1/2 mutations [55,114].