SNCA and Parkinson disease: In another FMT study, it was found that fecal transplants from PD individuals enhanced motor dysfunctions in an ASO (alpha-synuclein overexpressing) mice model, as indicated by four different motor function tests (i.e., beam transversal, pole descent, nasal adhesive removal, and hindlimb clasping reflex) and resulted in the development of several pathologic features commonly seen in PD [29].