The immunoreactivity of the main antioxidant enzymes, (i) catalase (CAT), (ii) superoxide dismutase 1 (SOD1), (iii) superoxide dismutase 2 (SOD2) and glutathione peroxidase 4 (GPX4), was analyzed at the colon level in mice treated for 21 days with BC. This evidence concerns the gene GPX4 and breast cancer.