Therefore, since most diabetic complications can be managed through the control of hyperglycemia [2], synthetic drugs such as insulin secretagogues from the sulfonylurea class, dipeptidyl peptidase-4 inhibitors, metformin, thiazolidinediones, glucagon-like peptide-1 agonists, and sodium-glucose cotransporter-2 inhibitors are widely used. Here, INS is linked to Hyperglycemia.