Kato et al. also demonstrated that siRNA targeting KIF11 suppressed the growth of highly invasive H460SM NSCLC tumour xenografts in mice [69], and Good et al. reported that Eg5 inhibition elicited potent anti-tumour efficacy in a patient-derived xenograft model of lung cancer [70]. This evidence concerns the gene KIF11 and non-small cell lung carcinoma.