Another group confirmed KIF3A’s tumour suppressive function in the human LUSC model SW900 and additionally discovered that knockdown led to hyperactivation of Wnt/β-catenin signalling, which was associated with increased proliferation, spheroid formation, migration, and expression of stemness markers in vitro as well as enhanced growth of the human LUSC tumour model SW900 in mice [234]. This evidence concerns the gene KIF3A and neoplasm.