In a study of AA (214 patients) and EA (2488 patients) men with PCa, patients were evaluated for P/LP variants in the DNA repair genes BRCA2, BRCA1, PALB2, ATM, RAD51C, CHEK2, PMS2, BARD1, BRIP1, MLH1, MSH2, MSH6, NBN, and RAD51D. The gene discussed is MSH2; the disease is posterior cortical atrophy.