An MRI showed no residual tumor postoperatively, and the hyperthyroidism was normalized, but the GH and IGF-I levels were not completely normalized (GH 1.71 ng/mL; IGF-I 291 ng/mL, SD score 2.8); therefore, a long-acting somatostatin analogue (10 mg/month) was initiated, following which GH and IGF-1 were well controlled. This evidence concerns the gene IGF1 and hyperthyroidism.