ERBB2 and breast cancer: The KPNA2 transcript levels were lower in Luminal A BC patients and significantly compared with Luminal B HER2 negative (p< 0.0001), with Luminal B HER2 positive (p< 0.0001), with HER-2 (p< 0.001), and with TNBC (p < 0.01) patients (Figure S2a).