Further analysis of the MMH cohort revealed that a high or low expression (transcript levels lower or higher than the cohort median) of KPNA2/FOXM1/CCNB1/CCNB2 is associated with ER, PR, HER2, and Ki67 status, molecular subtype, tumor grade, and AJCC stage (Table 2 and Table S2). This evidence concerns the gene ESR1 and neoplasm.