TBX19 and neoplasm: Similarly, TBX19 was significantly overexpressed in pituitary ACTH-secreting tumors (~18-fold higher than in pituitary) and lung ACTH-secreting tumors (~46-fold higher than in normal lung tissue and ~7.5-fold higher than in pituitary); however, it was not overexpressed in our pancreatic ACTH-secreting tumor sample.