Oncogenic lncRNAs promote cell proliferation (e.g., REG1CP—colorectal cancer, SATB2-AS1—osteosarcoma, MALAT1—liver and lung cancer), cell invasion (e.g., PCAT19—prostate cancer, HOTAIR—prostate cancer), and metastasis (e.g., PCAT19—prostate cancer, SATB2-AS1—osteosarcoma, MALAT1), and they may also contribute to evading the immune response (e.g., LINKA) and apoptosis (e.g., XIST—breast cancer, MALAT1—liver cancer), or promote the degradation of tumor suppressors (e.g., LINKA) [189,190,191,192,193,194,195,196,197]. This evidence concerns the gene HOTAIR and neoplasm.