However, Harrison et al. suggested that FH deficiency in leiomyomas might have been over-interpreted because of their morphological features like uterine leiomyosarcomas (uLMS) (hypercellularity and tendency for symplastic nuclear atypia), leading pathologists to misdiagnose benign leiomyomas as malignant leiomyosarcomas [1]. The gene discussed is FH; the disease is leiomyosarcoma.