According to the WHO-EORTC classification, CTCL includes mycosis fungoides (MF), MF variants, Sézary syndrome (SS), adult T-cell leukemia/lymphoma (ATLL), primary cutaneous CD30+ LPDs, subcutaneous panniculitis-like T-cell lymphoma (SPTCL), extranodal NK/T-cell lymphoma-nasal type (ENKTCL-NT), chronic active EBV infection, primary cutaneous peripheral T-cell lymphoma (PTCL)-rare subtypes, and primary cutaneous PTCL-not otherwise specified (PTCL-NOS). This evidence concerns the gene TNFRSF8 and adult T-cell leukemia/lymphoma.