MDM2 and breast cancer: Together with the over expression of mouse double minute 2 (MDM2), it has a role in BC via the augmentation of BC invasion and migration through negatively regulating P53 as well as tumor necrosis factor α (TNFα), which elicits inhibition of cell proliferation, induction of apoptosis, and even the enhancement of cell migration, as well as contributing to poor prognosis outcomes.