In addition, while this study did not incorporate subtype stratification analysis, single-cell RNA sequencing revealed that the elevated expression of core genes, including CDH1, VTN, and COL1A1, in fibroblasts and type II alveolar epithelial cells is strongly associated with the molecular characteristics of the UIP pattern [61,62]. This evidence concerns the gene COL1A1 and idiopathic pulmonary fibrosis.