The comparison between the three considered categories (N; N + V; N + UI) showed a reduced PPARγ expression in N + V and N + UI groups with respect to that detected in the N group, suggesting that reproductive pathologies, such as varicocele or urogenital infections, in cases where increased F2-IsoP and RvD1 levels indicate the presence OS and inflammation, can influence PPARγ expression. Here, PPARG is linked to varicocele.