For example, a study investigated the protective effects of GV1001, an anticancer vaccine with anti-inflammatory and antioxidant properties, in mitigating the impact of P. gingivalis-induced periodontal disease on atherosclerosis and Alzheimer’s disease (AD) in Apolipoprotein E (ApoE)-deficient mice. This evidence concerns the gene APOE and early-onset autosomal dominant Alzheimer disease.