Further analysis using the functional module of TIMER on TCGA transcriptome data from 458 patients with CRC showed a positive correlation between HDGF levels and several HR-related genes, including X-ray repair cross complementing 5 (XRCC5; Ku80), XRCC6 (Ku70), partner and localizer of BRCA2 (PALB2), BRCA1, BRCA2, retinoblastoma-binding protein 8 (RBBP8; CtIP), RPA2, and RAD51. The gene discussed is BRCA1; the disease is colorectal carcinoma.